A bioresorbable Chitosan-based nasal dressing recently approved by the FDA has drawn interest due

to Chitosan’s hydrophilic, antibacterial, and hemostatic properties, as well as its ability to minimize postop

adhesions, synechia, and crusting when in contact with mucosal membranes. Both of these materials

also possess the ability to act as a carrier for the targeted delivery of topical medications, such as

antibiotics and/or steroids, which have been shown to further enhance wound healing  Chitosan is a polysaccharide molecule derived from de-acylation of chitin from the exoskeletons of

crustaceans. Multiple biomedical applications and research in the military have shown the inherent

antibacterial and hemostatic properties of Chitosan, which improves wound healing for advanced

biomedical use

This study investigates and compares the wound healing and hemostatic characteristics, and patient

comfort factors of two bioresorbable MM dressings, a Chitosan-based polymer (PosiSep X) and a

well-known fully synthetic polyurethane foam sponge (NasoPore) in patients recovering from

 Conclusions

A Chitosan-based biodegradable MM dressing offers a statistically significant advantage over a

polyurethane-based biodegradable polymer with respect to wound healing characteristics measured by

degree of crusting, amount of retained implant, epistaxis, and infection in patients undergoing ESS.

Furthermore, the Chitosan dressing was also superior based on the decreased requirement for, and extent

of, post-operative endoscopic debridement, and a lower complication rate as measured by the need for

additional corrective procedures and/or medical intervention. Our study is consistent with the current

scientific literature regarding Chitosan-based biomaterials that offer enhanced biocompatibility and are

hydrophilic, bacteriostatic, and hemostatic

International name- POSISEP

Manufacturer- - hemostasis,LLC